Endocrine Abstracts

Background: Reduced GLUT4 expression in insulin-sensitive tissues, insulin resistance, inflammation, nonalcoholic steatohepatitis (NASH) and hypertension are pathophysiologic changes expected in metabolic syndrome animal models.Aims: To fully characterize the development and maintenance of metabolic syndrome features over time (GLUT4 in insulin-sensitive tissues, insulin resistance, inflammation, blood pressure and liver changes) in spontaneously hyperte...